EC 247-103-9 Pharma Intermediates Flammable Medicine Intermediate

Name: N,O-Bis(trimethylsilyl)trifluoroacetamide

Other names: Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate

N,O-bis-TMS-trifluoroacetamide; N,O-Bis(trimethylsilyl)trifluoroacetamide; N,O-BSTFA

Molecular formula: C₈H₁₈F₃NOSi₂

Molecular weight: 257

CAS: 25561-30-2

EC Number: 247-103-9

Identified uses: Industrial and scientific research uses, Pharmaceutical intermediate or medicine intermediate

Physical and chemical properties

Appearance: Clear to yellowish clear liquid

Melting point/freezing point: -41°C(lit.)

Flash point 24°C

Solubility In water: hydrolyses

Density and/or relative density 0.969g/mLat 25°C(lit.)

Hazard identification

Classification of the substance or mixture

Flammable liquids, Category 2

Skin irritation, Category 2

Eye irritation, Category 2

GHS label elements

Signal word: Danger

Hazard statement(s)

H225 Highly flammable liquid

H315 Causes skin irritation

H319 Causes serious eye irritation

Safety instructions:

S16: Keep away from ignition sources.

S26: If splashed in eyes, flush with plenty of water and get medical attention immediately.

S45: if cause an accident or feel discomfort when handing chemicals, seek medical help immediately (preferably with the product container label).

S36/37/39: Wear appropriate protective clothing, gloves and use protective glasses or face shield.

Storage

Store in a well-ventilated place. Keep cool(2°C--8°C).

Disposal

Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Description of necessary first-aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and seek medical care immediately..

Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Seek medical care immediately.

Following eye contact

Rinse with pure water for at least 15 minutes. Seek medical care immediately.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Seek medical care immediately..

Product application

Pharmaceutical intermediate or medicine intermediate. Derivatization reagent for the detection of melamine by GC-MS or GC-MS/MS.